BDBM50204134 (S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine::CHEMBL246284

SMILES Fc1cccc(Cn2ncc3cc(Nc4ncnn5ccc(COC[C@@H]6CNCCO6)c45)ccc23)c1

InChI Key InChIKey=UEJUKJJOSDYORR-QHCPKHFHSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204134   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204134((S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((mor...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant cytoplasmic HER2 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204134((S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((mor...)
Affinity DataIC50:  55nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50204134((S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((mor...)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant HER2 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed